SAN DIEGO, CA - (November 3, 2000) - Privately held Structural Bioinformatics, Inc. (SBI) today announced that Mr. Michael "Mick" Savage has been appointed to SBI's Management Advisory Board, where he will provide strategic advice and counsel with respect to marketing of the Company's products and other related strategic business issues.

Mr. Savage previously served as President and Chief Executive Officer of Molecular Simulations Inc. (MSI), a leading provider of molecular modeling and simulation software and services for both life and materials science research. He was instrumental in bringing MSI to the forefront of developing computer assisted drug discovery software for preclinical research and development. Through a combination of internal growth and acquisitions, Mr. Savage guided MSI to a sixty-fold increase in revenues over eight years.

Prior to MSI, Mr. Savage served in several key senior management positions in sales and marketing. His experience and industry focus within the science and information technology communities have contributed to the success in his roles with Molecular Design Ltd. and Beckman Instruments. In addition, Mr. Savage currently serves on the Boards of a number of private companies.

"Mr. Savage has been a successful marketer of scientific software products and is widely regarded as one of the top strategic marketing minds in our industry," said Dr. Edward T. Maggio, Chairman, President and Chief Executive Officer of SBI. "His unique insight into our industry will play an integral role to our future success."

"SBI is a true first mover in the field of structural proteomics, having developed a leading reputation for large-scale protein structure prediction and analysis over the past three years," said Mick Savage. "The scientific community is now beginning to accept and demand the types of products offered by SBI, especially their extensive database of high-quality protein models. Of particular note is that SBI's internal drug discovery programs have proven the utility of these protein models. It is this experimental validation which clearly differentiates SBI's products in the market."

Structural Bioinformatics is a world leader in computational proteomics -- the large-scale generation and use of protein structure and protein structural information. The Company has developed advanced technologies to generate highly refined three-dimensional structural models of proteins from primary genetic information and commercializes these technologies through its structural database products and through drug discovery collaborations with leading pharmaceutical companies. SBI has offices in San Diego, CA and Hørsholm, Denmark.