SAN DIEGO, CA - (November 1, 2000) - Privately held Structural Bioinformatics, Inc. (SBI) today announced that Mr. Joe Fanelli has joined the Executive Management Team as its Vice President of Sales & Marketing. Mr. Fanelli will be responsible for the worldwide sales and marketing of SBI's proprietary 3-D Structural Protein Database Products and Population Variant Database Series. The continued global expansion of SBI's sales and marketing infrastructure will be a top priority.

Prior to joining SBI, Mr. Fanelli held the position of Vice President of Sales & Marketing for Base4 Inc., where he was responsible for commercializing the company's knowledge management software. His extensive experience building and directing technical sales and marketing teams are of major importance to SBI in bringing its advanced technology to the scientific community. Mr. Fanelli has held senior management positions in Business Development, Sales and Operations at Quantum Biotechnologies, Beckman Instruments, Cetus, Microgenics and Cangene.

"Over the past few years, SBI has become a world leader in computational proteomics and in the modeling of accurate, high-quality 3-D protein structures," said Joe Fanelli. "I am pleased to join SBI to expand its leadership position in drug discovery collaborations through the commercialization of novel database technologies and 3-D Database Management Systems."

"Mr. Fanelli brings a unique set of industry specific sales, marketing and management skills necessary for realizing the enormous potential that lies before us in structural proteomics as we fulfill our strategic business objectives," said Dr. Edward T. Maggio, Chairman, President and Chief Executive Officer. "I am delighted that Mr. Fanelli has joined SBI's Management Team."

Structural Bioinformatics is a world leader in computational proteomics -- the large-scale generation and use of protein structure and protein structural information. The Company has developed advanced technologies to generate highly refined three-dimensional structural models of proteins from primary genetic information and commercializes these technologies through its structural database products and through drug discovery collaborations with leading pharmaceutical companies. SBI has offices in San Diego, CA and Hørsholm, Denmark.