ROCKVILLE, MD - (September 12, 2000) - InforMax, a leading global provider of bioinformatics software solutions for accelerated drug discovery, and Structural Bioinformatics, Inc., a world leader in computational proteomics, today announced that SBI's proprietary database content of atomic resolution 3-D protein models will be offered to GenoMax^TM customers under the SBD^TM brand name. The SBD^TM is comprised of thousands of structural models of proteins from more than 200 distinct families.

"3-D protein structure provides great insight to any biological researcher but particularly to molecular biologists who are trying to identify sites critical to function," said Alex Titomirov, InforMax President and Chief Executive Officer. "SBI's database of modeled proteins provides immediate access to high-quality models that have been vetted by SBI's protein modeling experts to help guide scientists' work in the laboratory. We think this is an excellent resource that we can provide to our customers."

"We are pleased to be working with InforMax," said Dr. Edward T. Maggio, Chairman, President and Chief Executive Officer of SBI. "The GenoMax^TM-SBD^TM product combination is uniquely positioned to provide overwhelming access to the protein structural information demanded by the industry."

About GenoMax^TM
  GenoMax^TM is an enterprise bioinformatics system that facilitates high-speed analysis of both public and proprietary genetic data sets within the security of the corporate firewall. GenoMax^TM offers speed, security, and scalability through the employment of client-server architecture, Oracle^® relational databases, and a sophisticated Java-based graphical user interface. To complete the delivery of a High Throughput Research (HTR^TM) environment, InforMax expects to introduce a series of GenoMax^TM modules in the next 12 months. These new modules will include Gene Expression, EST Clustering, Genome Viewing, 3D-Structure Prediction, SNP Analysis and Protein-Protein Interaction Analysis.

About InforMax, Inc.
  Headquartered in Rockville, Md., InforMax, Inc. is a global leader in bioinformatics, providing solutions for the analysis and interpretation of genomic, proteomic and other biomolecular data. InforMax, founded in 1990 by Dr. Alex Titomirov, enables over 20,000 researchers worldwide to achieve greater insights into genetic function through biological data mining and integrated genomics analysis. Presently, InforMax offers Vector NTI Suite desktop sequence analysis software and GenoMax^TM enterprise bioinformatics system. Additional information about InforMax can be found at the company's site on the World Wide Web at www.informaxinc.com.

About Structural Bioinformatics, Inc.
  Structural Bioinformatics is a world leader in computational proteomics--the large-scale generation and use of protein structure and protein structural information. The Company has developed advanced and proprietary computational technologies to generate highly refined three-dimensional structural models of proteins from primary gene sequence data that compare well with crystal structures. SBI uses this and other protein structural data to perform primary drug-discovery screening in silico on millions of compounds in a matter of hours, increasing the "hit rate," and reducing the cost of chemical synthesis, by a factor of a thousandfold. SBI also offers two subscription protein structural database products to accelerate lead discovery and optimization and to permit the incorporation of structural pharmacogenomics information early-on in the drug development process: SBdBase^TM, composed of thousands of structural models of proteins from more than 200 distinct families; and SVdBase^TM, a growing series of structural variant database modules each containing thousands of patient-derived structural polymorphism models for medically important genes, such as HIV reverse transcriptase and HIV protease.